Title of article
Synthesis of substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles by intramolecular nitrilimine cycloaddition
Author/Authors
Winters، نويسنده , , Michael P. and Teleha، نويسنده , , Christopher A. and Sui، نويسنده , , Zhihua، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
2150
To page
2153
Abstract
Both substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles have been synthesized by the 3+2 intramolecular dipolar cycloaddition of nitrilimines to alkynes. This cyclization has been extended to more versatile 3-bromo derivatives by the use of alkynylbromides as dipolarophiles.
Keywords
Nitrilimine , Intramolecular 3+2 dipolar cycloaddition , Tetrahydrocyclopentylpyrazoles , Tetrahydropyrrolopyrazoles , N-type calcium channel
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888783
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