Title of article
An expedient one-pot sequential five-component synthesis of highly substituted spiro-pyrrolidine heterocycles
Author/Authors
Gavaskar، نويسنده , , D. and Raghunathan، نويسنده , , R. and Suresh Babu، نويسنده , , A.R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
2217
To page
2220
Abstract
An expedient one-pot sequential five-component synthesis of highly substituted pyrrolidine heterocycles involving [3+2]-cycloaddition of azomethine ylides as the key step is described. The protocol provides a mild reaction condition, high yield of the products, high regioselectivity and operational simplicity to assemble complex structural entity in a single operation. The structure of the product was confirmed by spectroscopic and single crystal X-ray analysis.
Keywords
Multicomponent reaction (MCR) , Azomethine ylide , cycloaddition , Spiro-heterocycle , pyrrolidine
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888815
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