Title of article :
Nano-copper catalyzed three-component reaction to construct 1,4-substituted 1,2,3-triazoles
Author/Authors :
Huang، نويسنده , , Lina and Liu، نويسنده , , Wei and Wu، نويسنده , , Juncheng and Fu، نويسنده , , Ying and Wang، نويسنده , , Kehu and Huo، نويسنده , , Congde and Du، نويسنده , , Zhengyin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
Three-component reaction of alkyl halides, sodium azide with terminal alkynes can be catalyzed by nano-copper particles under ambient conditions. A series of 1,4-disubstituted-1,2,3-triazoles were obtained regioselectively by this one-pot strategy. Nano copper can be reused at least three times without significant deactivation.
Keywords :
Copper nanoparticles , phenylacetylene , cycloaddition , click chemistry , multicomponent reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
