Author/Authors :
Power، نويسنده , , Derek G. and Galvin، نويسنده , , David J. and Cuffe، نويسنده , , Sinead and McVey، نويسنده , , Gerald P. and Mulholland، نويسنده , , Paul J. and Farrelly، نويسنده , , Cormac and Delaney، نويسنده , , David W. and OʹByrne، نويسنده , , Kenneth J.، نويسنده ,
Abstract :
Penile cancer is rare and receives little public attention. There are few treatment options for advanced disease. The most active regimen to date is a combination of bleomycin, methotrexate, and cisplatin. However the treatment-related mortality is 11% and hence this combination has not been adapted as a standard of care. We report two cases of advanced penile cancer where a sustained palliative response was observed with combination chemotherapy using cisplatin and gemcitabine. Our experience demonstrates that this is a well tolerated regimen active in this setting.
Keywords :
penile , Metastatic , radiotherapy , cancer , chemotherapy