• Title of article

    Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives

  • Author/Authors

    Shao، نويسنده , , Li-Dong and Xu، نويسنده , , Jun and Gao، نويسنده , , Xiu and He، نويسنده , , Juan and Zhao، نويسنده , , Yu and Peng، نويسنده , , Li-Yan and Luo، نويسنده , , Huai-Rong and Xia، نويسنده , , Chengfeng and Zhao، نويسنده , , Qin-Shi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2014
  • Pages
    4
  • From page
    3414
  • To page
    3417
  • Abstract
    Intramolecular hetero-DA reaction and unexpected retro-aldol like ring opening reaction were performed. As a result, six derivatives with different skeletons of vibsane-type diterpenoids were synthesized from vibsanin B within three steps. Moreover, compounds 2, 3, and 6 enhanced the neurite outgrowth of NGF-mediated PC12 cells.
  • Keywords
    Intramolecular hetero-DA reaction , Retro-aldol like ring opening reaction , Vibsanin B , Neurite outgrowth promoting
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2014
  • Journal title
    Tetrahedron Letters
  • Record number

    1889705