Title of article
Domino synthesis of 1,3-diynes from 1,1-dibromoalkenes: a Pd-catalyzed copper-free coupling method
Author/Authors
Rao، نويسنده , , Maddali L.N. and Dasgupta، نويسنده , , Priyabrata and Ramakrishna، نويسنده , , Boddu S. and Murty، نويسنده , , Venneti N.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
3529
To page
3533
Abstract
Pd-catalyzed domino synthesis of 1,3-diynes was accomplished using 1,1-dibomoalkenes under copper-free coupling conditions. This domino procedure involves base mediated in situ generation of 1-bromoalkyne and its subsequent coupling to give 1,3-diyne. The optimized copper-free coupling method afforded good to high yields of symmetrical 1,3-diynes in a one-pot operation.
Keywords
Couplings , copper-free , 3-diynes , Pd-Catalyzed , 1-Dibromoalkenes , 1 , 1 , DOMINO
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1889769
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