Author/Authors :
Vujjini، نويسنده , , Satish Kumar and Datla، نويسنده , , V.R. Krishnam Raju and Badarla، نويسنده , , Krishna Rao and Vetukuri، نويسنده , , V.N.K.V. Prasada Raju and Bandichhor، نويسنده , , Rakeshwar and Kagga، نويسنده , , Mukkanti and Cherukupally، نويسنده , , Praveen، نويسنده ,
Abstract :
Total synthesis of antidepressant drug, agomelatine is reported. Regio selective Friedel–Crafts acylation followed by Willgerodt–Kindler reactions is used as the key steps for the synthesis of agomelatine.
Keywords :
Antidepressant drug , Regio selectivity , Agomelatine , Willgerodt–Kindler reaction , Friedel–Crafts acylation
