Title of article :
Toward the stereoselective synthesis of C1–C23 fragment of spirastrellolide B
Author/Authors :
Rajesh، نويسنده , , Akkapalli and Sharma، نويسنده , , Gangavaram V.M. and Damera، نويسنده , , Krishna، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A convergent synthesis of the protected C(1)–C(23) fragment 4 of the targeted natural product spirastrellolide B is described. The key step of the synthesis is cross metathesis (CM) and TBAF promoted oxa-Michael to construct tetrahydropyran moiety.
Keywords :
Sharpless asymmetric epoxidation , Oxa-Michael addition , Hydroxylalkynylation , Cross metathesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
