Title of article
2,6-Bis(diphenylphosphino)pyridine: a simple ligand showing high performance in palladium-catalyzed CN coupling reactions
Author/Authors
Nadri، نويسنده , , Shirin and Rafiee، نويسنده , , Ezzat and Jamali، نويسنده , , Sirous and Joshaghani، نويسنده , , Mohammad، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
4098
To page
4101
Abstract
The use of commercially available 2,6-bis(diphenylphosphino)pyridine as a ligand in conjunction with K2CO3, DMAc and TBAB is an effective method for the palladium-catalyzed CN coupling of a variety of aryl halides with anilines, N-heterocyclic aromatic amines, and a cyclic secondary amine. The reactions proceed in good to excellent yield (up to 98%) while the loading of Pd(OAc)2 was as low as 0.025 mol %.
Keywords
PALLADIUM , Phosphine ligand , Buchwald–Hartwig reaction , CN coupling
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890131
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