Author/Authors :
Gautam، نويسنده , , Vibha and Kagita، نويسنده , , Veera Babu and Nambiar، نويسنده , , Sudhir and Phaneendra، نويسنده , , Gutala and Manjunatha، نويسنده , , Sulur G. and Ramasubramanian، نويسنده , , Sridharan and Suresh Babu، نويسنده , , M. and Keshwan، نويسنده , , Jaikumar and Bhagat، نويسنده , , Sagar and Prakash، نويسنده , , Ravindran and Puranik، نويسنده , , Ramachandra، نويسنده ,
Abstract :
A simple synthetic approach has been developed towards one pot synthesis of 2-imidazolines under mild acidic conditions from N-acetyl glucosamine via reductive amination followed by dehydrative cyclization. Synthetic studies were explored in detail with different amines and sugar derivatives. While the conversion was good, the corresponding substituted imidazolines were obtained in moderate yields.
Keywords :
Dehydrative cyclization , Stereospecific , 2-Imidazolines , 2-Aminosugars