Title of article
Diastereoselective organocatalytic Mannich access to azacyclic system en route to lyconadin A
Author/Authors
Cormier، نويسنده , , Morgan and Jean، نويسنده , , Alexandre and Blanchet، نويسنده , , Jérôme and Rouden، نويسنده , , Jacques and Maddaluno، نويسنده , , Jacques and De Paolis، نويسنده , , Michael، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
5074
To page
5077
Abstract
Organocatalytic and stereoselective Mannich coupling of hindered and chiral cyclohexylcarboxaldehyde is described for a synthetic approach to the pyrrolidine core of lyconadin A. The strategy led concisely and stereoselectively to complex azaheterocyclic system containing up to five stereocenters.
Keywords
Azaheterocyclic system , spirocycles , Diastereoselective Mannich , H-bonding , organocatalysis
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890589
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