Author/Authors :
Downey، نويسنده , , C. Wade and Covington، نويسنده , , Sarah E. and Obenschain، نويسنده , , Derek C. and Halliday، نويسنده , , Evan and Rague، نويسنده , , James T. and Confair، نويسنده , , Danielle N.، نويسنده ,
Abstract :
para-Methoxybenzyl methyl ether acts as an alkylating agent for thiols in the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base in good yields (58–96%). Aryl ketones are alkylated under similar conditions, probably through an enol silane intermediate, also in high yields (67–95%). The active alkylating species is likely a p-methoxybenzyl cation.
Keywords :
Methyl ethers , Silyl triflates , Alkylation , Enol silanes
