Author/Authors :
Martins، نويسنده , , Lucimara J. and Ferreira، نويسنده , , Bruno R.V. and Almeida، نويسنده , , Wanda P. and Lancellotti، نويسنده , , Angelo Marcelo and Coelho، نويسنده , , Fernando، نويسنده ,
Abstract :
We describe an improved protocol for the synthesis of spiro-hexadienones from Morita–Baylis–Hillman adducts. Solvent modification and temperature resulted in a significant increase in the yield. This protocol was used to synthesize mono- and dibrominated spiro-hexadienones in good overall yields. This report is the first to describe the synthesis of halogenated spiro-hexadienones from Morita–Baylis–Hillman adducts.
Keywords :
hypervalent iodine , Morita–Baylis–Hillman , Spiro-hexadienones , Heck reaction , Brominated compounds
