Author/Authors :
Cheng، نويسنده , , Yuan-Bin and Lan، نويسنده , , Chih-Chin and Liu، نويسنده , , Wei-Chun and Lai، نويسنده , , Wan-Chun and Tsai، نويسنده , , Yu-Chi and Chiang، نويسنده , , Michael Y. and Wu، نويسنده , , Yang-Chang and Chang، نويسنده , , Fang-Rong، نويسنده ,
Abstract :
A chemical investigation of Zoanthus kuroshio has yielded two new alkaloids, kuroshines A (1) and B (2). The compounds possess a densely functionalized ring system on the basis of the zoanthamine frames. The structures of 1 and 2 were elucidated through interpretation of spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and ROESY). The absolute stereochemistry of 1 was further confirmed by an X-ray single crystallographic analysis using a mirror Cu-Kα radiation.
Keywords :
Kuroshine , Alkaloids , marine natural products , Zoanthus kuroshio
