Title of article :
Synthesis of arylsulfonyl-quinones and arylsulfonyl-1,4-diols as FabH inhibitors: Pd-catalyzed direct C-sulfone formation by CS coupling of quinones with arylsulfonyl chloride
Author/Authors :
Ge، نويسنده , , Bingyang and Wang، نويسنده , , Dawei and Dong، نويسنده , , Weifu and Ma، نويسنده , , Piming and Li، نويسنده , , Yongliang and Ding، نويسنده , , Yuqiang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
The Pd-catalyzed direct C-sulfone formation by CS coupling of quinones with arylsulfonyl chloride has been developed. This methodology provides an effective, convenient method for the synthesis of arylsulfonyl-quinones and arylsulfonyl-1,4-diols, which are potent inhibitors of FabH.
Keywords :
Coupling , quinones , Sulfonyl-1 , 4-diols , FabH inhibitors , C-sulfone
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
