Title of article :
Catalyst- and chromatography-free synthesis of pyrrole-substituted indolinone derivatives in water
Author/Authors :
Ahmad، نويسنده , , Nazim A.A. and Rokade، نويسنده , , Sunil M. and Garande، نويسنده , , Ashok M. and Bhate، نويسنده , , Prakash M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
Pyrrole-substituted indolinone derivatives were synthesized by the reaction of 4-hydroxyproline and isatin derivatives in water under catalyst-free conditions. The main advantages of this protocol besides the use of water as a solvent include short reaction time, practical simplicity, and high yield.
Keywords :
trans-4-Hydroxy-l-proline , green chemistry , 3-(Pyrrol-1-yl)-indolin-2-one , Isatin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
