Title of article :
PhI(OAc)2 and BF3–OEt2 mediated heterocyclization: metal-free synthesis of pyrimidine-annulated oxazolines
Author/Authors :
Mondal، نويسنده , , Biplab and Hazra، نويسنده , , Somjit and Naktode، نويسنده , , Kishor and Panda، نويسنده , , Tarun K. and Roy، نويسنده , , B.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A simple high yielding and highly efficient synthesis of oxazoline ring fused with uracil moiety is reported. Hypervalent iodine (PIDA) in the presence of BF3–OEt2 generates an effective electrophile to activate uracil C5–C6 double bond leading to heterocyclization.
Keywords :
oxazoline , hypervalent iodine , Pyrimidine , BF3–OEt2 , cyclization , PhI(OAc)2
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
