Title of article :
Microwave-assisted chemoselective synthesis of novel pyrazolo[3,4-b]thieno[3,4-e]pyridines: substitution induced axial chirality
Author/Authors :
Rani، نويسنده , , Mani Anusha and Jeyachandran، نويسنده , , Veerappan and Muthu، نويسنده , , Muthumani and Sivakolunthu، نويسنده , , Subbiah and Kumar، نويسنده , , Raju Ranjith Kumar، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A microwave-assisted chemoselective synthesis of novel pyrazolo[3,4-b]thieno[3,4-e]pyridines has been achieved via tandem Michael addition–cyclization–tautomerization–oxidative aromatization sequence of reactions. Compounds with ortho-substituted phenyl rings exhibited axial chirality due to restricted rotation around C–C single bond.
Keywords :
4-e]pyridine , axial chirality , Tandem reaction , microwave irradiation , Chemoselective Michael addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
