• Title of article

    Synthesis and cell phototoxicity of a triply bridged fused diporphyrin appended with six thioglucose units

  • Author/Authors

    Singh، نويسنده , , Sunaina and Aggarwal، نويسنده , , Amit and Bhupathiraju، نويسنده , , N.V.S. Dinesh K. and Newton، نويسنده , , Brandon and Nafees، نويسنده , , Ahmad and Gao، نويسنده , , Ruomei and Drain، نويسنده , , Charles Michael، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2014
  • Pages
    4
  • From page
    6311
  • To page
    6314
  • Abstract
    A triply bridged fused diporphyrin appended with six thioglucose units is reported. This new, chemically, and photochemically stable amphiphilic compound is taken up by breast cancer cells and causes cell death upon light exposure. Photophysical studies reveal absorption bands in the near IR region, and photosensitized formation of singlet oxygen in high quantum yields.
  • Keywords
    Porphyrin , Thioglucose , fluorescence , click chemistry , photodynamic therapy
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2014
  • Journal title
    Tetrahedron Letters
  • Record number

    1891176