Author/Authors :
Singh، نويسنده , , Sunaina and Aggarwal، نويسنده , , Amit and Bhupathiraju، نويسنده , , N.V.S. Dinesh K. and Newton، نويسنده , , Brandon and Nafees، نويسنده , , Ahmad and Gao، نويسنده , , Ruomei and Drain، نويسنده , , Charles Michael، نويسنده ,
Abstract :
A triply bridged fused diporphyrin appended with six thioglucose units is reported. This new, chemically, and photochemically stable amphiphilic compound is taken up by breast cancer cells and causes cell death upon light exposure. Photophysical studies reveal absorption bands in the near IR region, and photosensitized formation of singlet oxygen in high quantum yields.
Keywords :
Porphyrin , Thioglucose , fluorescence , click chemistry , photodynamic therapy