Author/Authors :
Manjunatha، نويسنده , , Sulur G. and Bachu، نويسنده , , Sreekanth and Gautam، نويسنده , , Vibha and Kumari، نويسنده , , Mohana and Nambiar، نويسنده , , Sudhir and Ramasubramanian، نويسنده , , Sridharan and Puranik، نويسنده , , Ramachandra، نويسنده ,
Abstract :
A simple and efficient methodology for the synthesis of 5-amino-quinazolines and 4-amino-indoles via Semmler–Wolff aromatisation reaction has been carried out. The oximation of keto intermediates followed by Semmler–Wolff aromatisation using acetic anhydride and a catalytic amount of sodium iodide in xylene provided the desired quinazolines and indoles.
Keywords :
5-Acetamido-2-aryl-quinozoline , 4-Acetamido N-alkyl/arylindole , Semmler–Wolff aromatisation , Sodium iodide , Acetic anhydride
