Title of article
Vincamajorines A and B, monoterpenoid indole alkaloids with new carbon skeletons from Vinca major
Author/Authors
Zhang، نويسنده , , Zhijun and Yang، نويسنده , , Jing and He، نويسنده , , Juan and Wu، نويسنده , , Xing-De and Shao، نويسنده , , Li-Dong and Li، نويسنده , , Yan and Huang، نويسنده , , Sheng-Xiong and Li، نويسنده , , Rong-Tao and Zhao، نويسنده , , Qin-Shi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
6490
To page
6494
Abstract
Two new monoterpenoid indole alkaloids, vincamajorines A (1) and B (2), were isolated from Vinca major. Their structures were elucidated by means of 1D and 2D NMR, and HREIMS spectroscopic data. The relative and absolute configurations were deduced by comparing the experimental 13C NMR, ECD spectra, and OR data with those theoretically calculated. Vincamajorine A (1) represents a new C20 carbon skeleton arranged compactly in seven rings, and vincamajorine B (2) is an alkaloid with an unprecedented 6/5/7/5/6 pentacyclic ring system. A possible biosynthetic pathway was also proposed for the formation of 1 and 2.
Keywords
quantum chemical calculations , Vinca major , Monoterpenoid indole alkaloids
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891259
Link To Document