Title of article
Metal-mediate reactions based formal synthesis of triptonide and triptolide
Author/Authors
Xu، نويسنده , , Hongtao and Tang، نويسنده , , Huanyu and Feng، نويسنده , , Huijin and Li، نويسنده , , Yuanchao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
7118
To page
7120
Abstract
A formal synthesis of triptolide and triptonide has been achieved based on metal-mediate reactions. Specially, Noyori’s ruthenium catalyzed enantioselective transfer hydrogenation, indium(III) catalyzed cationic polyene cyclization, palladium catalyzed carbonylation, rhodium catalyzed double bond migration, and palladium catalyzed ortho sp2 C–H bond oxygenation reactions served as convenient entry points for the preparation of the tetracyclic building blocks and the C14 hydroxyl group.
Keywords
Synthesis , Triptolide , Diterpenoid , Metal , Triptonide
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1893571
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