Author/Authors :
Wang، نويسنده , , John C and Aucoin-Barry، نويسنده , , Denise and Manuelian، نويسنده , , Deborah and Monbouquette، نويسنده , , Rachele and Reisman، نويسنده , , Mark R. Gray، نويسنده , , William A. Block Jr.، نويسنده , , Peter C and Block، نويسنده , , Elizabeth H and Ladenheim، نويسنده , , Marc A. Simon، نويسنده , , Daniel I، نويسنده ,
Abstract :
We report the incidence of aspirin nonresponsiveness in a prospective, multicenter registry (n = 422 patients) to be 23% using the Ultegra Rapid Platelet Function Assay-ASA, and determined a history of coronary artery disease to be associated with twice the odds of being an aspirin nonresponder (odds ratio 2.01, 95% confidence interval 1.189 to 3.411, p = 0.009). Further prospective studies are needed to correlate aspirin nonresponsiveness to adverse clinical events.