Author/Authors :
Koster، نويسنده , , Andreas and Spiess، نويسنده , , Bruce and Chew، نويسنده , , Derek P. and Krabatsch، نويسنده , , Thomas and Tambeur، نويسنده , , Luc and DeAnda، نويسنده , , Abe and Hetzer، نويسنده , , Roland and Kuppe، نويسنده , , Hermann and Smedira، نويسنده , , Nicholas G. and Lincoff، نويسنده , , A.Michael، نويسنده ,
Abstract :
We investigated the use of bivalirudin as an anticoagulant therapy during cardiopulmonary bypass in 20 patients who underwent coronary artery bypass grafting. Primary end points consisted of clinical outcome data, whereas secondary end points focused on blood loss, transfusions, pharmacokinetics, and monitoring. Our data provide the first evidence of clinical feasibility of anticoagulation with bivalirudin during cardiopulmonary bypass.
