Author/Authors :
Kandzari، نويسنده , , David E. and Granger، نويسنده , , Christopher B. and Simoons، نويسنده , , Maarten L. and White، نويسنده , , Harvey D. and Simes، نويسنده , , John and Mahaffey، نويسنده , , Kenneth W. and Gore، نويسنده , , Joel GR Weaver، نويسنده , , W.Douglas and Longstreth Jr.، نويسنده , , William T. and Stebbins، نويسنده , , Amanda and Lee، نويسنده , , Kerry L. and Califf، نويسنده , , Rob، نويسنده ,
Abstract :
Of 592 patients in the Global Utilization of Streptokinase and tPA for Occluded Arteries-I trial who had a stroke during initial hospitalization, the risk for intracranial hemorrhage was significantly greater in those with recent facial or head trauma (odds ratio 13.0, 95% confidence interval 3.4 to 85.5); dementia was additionally associated with an increased risk for intracranial hemorrhage (odds ratio 3.4, 95% confidence interval 1.2 to 10.2). Because facial or head trauma may greatly influence treatment decisions, this risk factor should be incorporated into models designed to estimate the risks and benefits of fibrinolytic therapy.
