Author/Authors :
Vaudo، نويسنده , , Gaetano and Marchesi، نويسنده , , Simona and Siepi، نويسنده , , Donatella and Bagaglia، نويسنده , , Francesco and Paltriccia، نويسنده , , Rita and Pirro، نويسنده , , Matteo and Schillaci، نويسنده , , Giuseppe and Lupattelli، نويسنده , , Graziana and Mannarino، نويسنده , , Elmo، نويسنده ,
Abstract :
The relevance of homocysteine to brachial flow-mediated vasodilatation and carotid and femoral intima-media thickness was investigated in 192 patients with hypercholesterolemia. Low-density lipoprotein cholesterol and homocysteine levels predicted brachial flow-mediated vasodilatation, internal carotid mean intima-media thickness, and intima-media thickening at all femoral sites. Homocysteine levels seem to be an additional factor in the initial atherosclerotic damage of patients with hypercholesterolemia.