Author/Authors :
Kataoka، نويسنده , , Tetsuro and Hamasaki، نويسنده , , Shuichi and Ishida، نويسنده , , Sanemasa and Saihara، نويسنده , , Keishi and Okui، نويسنده , , Hideki and Fukudome، نويسنده , , Tsuyoshi and Shinsato، نويسنده , , Takurou and Mizoguchi، نويسنده , , Etsuko and Ninomiya، نويسنده , , Yuichi and Otsuji، نويسنده , , Yutaka and Minagoe، نويسنده , , Shinichi and Tei، نويسنده , , Chuwa، نويسنده ,
Abstract :
This study assessed the impact of coronary vascular adaptive remodeling and coronary vascular reactivity on myocardial ischemia in patients with hypertension and left ventricular hypertrophy. Myocardial ischemia is associated with impaired endothelium-independent vasodilation of resistance coronary arteries and increased minimal coronary resistance. These changes may occur in association with lumen reduction caused by attenuated adaptive remodeling in response to plaque accumulation.