Title of article :
Erythrocyte indexes, iron metabolism, and hyperhomocysteinemia in adults with cyanotic congenital cardiac disease
Author/Authors :
Kaemmerer، نويسنده , , Harald and Fratz، نويسنده , , Sohrab and Braun، نويسنده , , Siegfried L. and Koelling، نويسنده , , Klaus and Eicken، نويسنده , , Andreas and Brodherr-Heberlein، نويسنده , , Silke and Pietrzik، نويسنده , , Klaus and Hess، نويسنده , , John، نويسنده ,
Abstract :
A high percentage of cyanotic adults (37%) with cyanotic congenital cardiac disease (CCD) presented with depleted iron stores (13 of 52) or latent iron deficiency (6 of 52), even in a CCD center in which cyanotic patient phlebotomy is mostly avoided. In many of these patients, hypochromia and microcytosis was frequent, whereas hyperchromia and macrocytosis were relatively common.Furthermore, 50% of patients presented with hyperhomocysteinemia, possibly related to folate or B vitamin deficiencies, which may increase red blood cell size and color, explaining the lack of microcytosis and hypochromia in many cyanotic patients with iron deficiency.
