Title of article :
Effect of oral l-arginine on oxidant stress, endothelial dysfunction, and systemic arterial pressure in young cardiac transplant recipients
Author/Authors :
Lim، نويسنده , , D.Scott and Mooradian، نويسنده , , Stephen J. and Goldberg، نويسنده , , Caren S. and Gomez، نويسنده , , Carlen and Crowley، نويسنده , , Dennis C. and Rocchini، نويسنده , , Albert P. and Charpie، نويسنده , , John R.، نويسنده ,
Abstract :
Oral l-arginine therapy reverses endothelial dysfunction and attenuates high blood pressure in hypertensive cardiac transplant recipients. l-arginine corrects derangements in the vascular endothelial nitric oxide (NO)-dependent signaling pathway. Our data support the concept that cardiac transplant recipients use excess endogenous NO from l-arginine supplementation to buffer increased vascular oxidant stress.
