Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction

This study evaluated left ventricular diastolic function with Doppler echocardiography before and after statin therapy. Statin therapy worsened diastolic parameters in most patients; coenzyme Q10 supplementation in patients with worsening diastolic function with statin therapy improved parameters of diastolic function.