Author/Authors :
Phillips، نويسنده , , Michael and Boehmer، نويسنده , , John P. and Cataneo، نويسنده , , Renee N. and Cheema، نويسنده , , Taseer and Eisen، نويسنده , , Howard J. and Fallon، نويسنده , , John T. and Fisher، نويسنده , , Peter E. and Gass، نويسنده , , Alan and Greenberg، نويسنده , , Joel and Kobashigawa، نويسنده , , Jon and Mancini، نويسنده , , Donna and Rayburn، نويسنده , , Barry and Zucker، نويسنده , , Mark J.، نويسنده ,
Abstract :
The Heart Allograft Rejection: Detection with Breath Alkanes in Low Levels study evaluated a breath test for oxidative stress in heart transplant recipients, and we report here a mathematical model predicting the probability of grade 3 rejection. The breath test divided the heart transplant recipients into 3 groups: positive for grade 3 rejection, negative for grade 3 rejection, and intermediate. The test was 100% sensitive for grade 3 heart transplant rejection when the p value was ≥0.98, and 100% specific when the p value was ≤0.058; in the intermediate group, the breath test determined the probability of grade 3 rejection and the predictive value of the result.
