Author/Authors :
Costa، نويسنده , , Ricardo A. and Lansky، نويسنده , , Alexandra J. and Mintz، نويسنده , , Gary S. and Mehran، نويسنده , , Roxana and Tsuchiya، نويسنده , , Yoshihiro and Negoita، نويسنده , , Manuela and Gilutz، نويسنده , , Yael and Nikolsky، نويسنده , , Eugenia and Fahy، نويسنده , , Martin and Pop، نويسنده , , Ramona and Cristea، نويسنده , , Ecaterina and Carlier، نويسنده , , Stephane and Dangas، نويسنده ,
Abstract :
The purpose of this study was to report the angiographic findings of the first human evaluation of the everolimus-eluting stent (EES) for the treatment of noncomplex coronary lesions. Forty-two patients with de novo coronary lesions (2.75 to 4.00 mm vessels; lesion length, <18 mm) were prospectively randomized in a 2:1 ratio to receive either the EES (n = 27) or a metallic stent (n = 15). Baseline clinical and angiographic characteristics were similar among both groups. At 6-month follow-up, EES had a lower in-stent late lumen loss (0.10 ± 0.22 vs 0.85 ± 0.32 mm, p <0.0001) and in-segment diameter stenoses (20.7 ± 12.3% vs 37.0 ± 15.8%, p = 0.002). There was no in-stent restenosis with EES; however, 1 focal distal edge restenosis was present. There was 1 in-stent and 1 in-segment (proximal edge) restenosis in the metallic stent group. There was no stent thrombosis or aneurysm formation at follow-up in either group.
