Author/Authors :
Castro، نويسنده , , Pablo F. and Mc-Nab، نويسنده , , Paul and Quintana، نويسنده , , Juan Carlos and Bittner، نويسنده , , Alex and Greig، نويسنده , , Douglas and Vergara، نويسنده , , Ismael and Vukasovic، نويسنده , , José Luis and Corbalan، نويسنده , , Ramَn and Copaja، نويسنده , , Miguel and Dيaz-Araya، نويسنده , , Guillermo and Chiong، نويسنده , , Mario and Troncoso، نويسنده , , Rodrigo and Alca، نويسنده ,
Abstract :
Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 months of treatment with maximal tolerated doses of carvedilol. Patients with HF had significant ventricular dyssynchrony compared with a normal population. The 50th percentile of patients with the greatest dyssynchrony at baseline showed significant improvement in ventricular synchrony after receiving carvedilol, and this was correlated positively with a reduction in end-diastolic LV volumes.
