Author/Authors :
Robinson، نويسنده , , Christina R. and Martin، نويسنده , , Justin L. and Zhang، نويسنده , , Lily and Canham، نويسنده , , Russell M. and Abdullah، نويسنده , , Shuaib M. and Cigarroa، نويسنده , , Joaquin E. and Hillis، نويسنده , , L. David and Murphy، نويسنده , , Sabina A. and McGuire، نويسنده , , Darren K. and de Lemos، نويسنده , , James A. and Keeley، نويسنده , , Ellen C.، نويسنده ,
Abstract :
In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.
