Author/Authors :
Clavijo، نويسنده , , Leonardo C. and Pinto، نويسنده , , Tina L. and Kuchulakanti، نويسنده , , Pramod K. and Torguson، نويسنده , , Rebecca and Chu، نويسنده , , William W. and Satler، نويسنده , , Lowell F. and Kent، نويسنده , , Kenneth M. and Suddath، نويسنده , , William O. and Waksman، نويسنده , , Ron and Pichard، نويسنده , , Augusto D.، نويسنده ,
Abstract :
Contrast-induced nephropathy (CIN) is a common complication of coronary angiography that is associated with significant morbidity and mortality. Preexisting renal dysfunction is the most important risk factor for the development of CIN. A novel strategy of infusing 1 L of 5% dextrose immediately before catheterization is associated with a lower rate of CIN in those at high risk (creatinine clearance ≤60 ml/min). CIN occurred in 47 patients (5.7%) in the control group and 2 patients (1.4%) in the group treated with 5% dextrose. The relative risk decrease was 73% (p = 0.03). This is an effective, quick, and inexpensive method of improving outcomes in patients who undergo percutaneous coronary interventions.