Author/Authors :
Okamura، نويسنده , , Tomonori and Kadowaki، نويسنده , , Takashi and Sekikawa، نويسنده , , Akira and Murata، نويسنده , , Kiyoshi and Miyamatsu، نويسنده , , Naomi and Nakamura، نويسنده , , Yasuyuki and El-Saed، نويسنده , , Aiman and Kashiwagi، نويسنده , , Atsunori and Maegawa، نويسنده , , Hiroshi and Nishio، نويسنده , , Yoshihiko and Takamiya، نويسنده , , Tomoko and Kanda، نويسنده , , Hideyuki and ، نويسنده ,
Abstract :
Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAC) determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (≥46 g/day), and participants who were drinking ≥69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors.
