Title of article :
Exercise-Induced Hypertension, Endothelial Dysfunction, and Coronary Artery Disease in a Marathon Runner
Author/Authors :
Goel، نويسنده , , Radha and Majeed، نويسنده , , Farhan and Vogel، نويسنده , , Robert and Corretti، نويسنده , , Mary C. and Weir، نويسنده , , Matthew and Mangano، نويسنده , , Charles and White، نويسنده , , Charles and Plotnick، نويسنده , , Gary D. and Miller، نويسنده , , Michael، نويسنده ,
Abstract :
Aerobic activity performed on a regular basis is 1 of several lifestyle recommendations endorsed to reduce risk of coronary disease. However, 1 potential concern of arduous aerobic activity is exercise-induced hypertension. This is the first case to our knowledge, of accelerated coronary calcification in an otherwise asymptomatic middle-aged male marathon runner devoid of traditional cardiovascular risk factors. As a consequence of exercise-induced hypertension and associated oxidative stress, improvement of endothelial dysfunction occurred after antioxidant supplementation. In conclusion, vigorous aerobic activity in susceptible individuals may promote oxidative stress and coronary atherosclerosis.
