Author/Authors :
Hannan، نويسنده , , Edward L. and Zhong، نويسنده , , Ye and Berger، نويسنده , , Peter B. and Walford، نويسنده , , Gary P. Curtis، نويسنده , , Jeptha P. and Wu، نويسنده , , Chuntao and Venditti، نويسنده , , Ferdinand J. and Higgins، نويسنده , , Robert S.D. and Smith، نويسنده , , Craig R. and Lahey، نويسنده , , Stephen J. and King III، نويسنده , , Spencer B.، نويسنده ,
Abstract :
Several randomized controlled trials and observational studies have compared outcomes of percutaneous coronary interventions (PCIs) with drug-eluting stents (DESs) and coronary artery bypass grafting (CABG), but they have not thoroughly investigated the relative difference in outcomes for patients aged ≥75 years. In this study, a total of 3,864 patients receiving DES and CABG (1,932 CABG-DES pairs) with multivessel coronary disease were propensity matched using multiple patient risk factors and were compared with respect to 3 outcomes (mortality, stroke/myocardial infarction [MI]/mortality, and repeat revascularization) at 2.5 years with a mean follow-up of 18 months. The mortality rates (DES/CABG hazard ratio 1.06, 95% confidence interval 0.87 to 1.30) and the stroke/MI/mortality rates (DES/CABG hazard ratio 1.15, 95% confidence interval 0.97 to 1.38) for the 2 procedures were not significantly different. Repeat revascularization rates were significantly higher for patients who received DESs. In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
