Desolvation of enkephalin–H2O clusters ejected from a quickly heated film

Molecular dynamics simulations have been employed to investigate the volatilization of the enkephalin embedded in a rapidly heated H2O film. Simulations are performed for three different energy inputs, 103%, 89% and 69%, to vaporize the entire film. The cluster formed for each system undergoes a fast decomposition. The decomposition leads to a rapid temperature drop and proceeds differently for the different energy inputs. For 103% energy input, the explosive evaporation is the dominant process while, for 69% energy input, the normal evaporation plays a significant role in the cluster decomposition.