Author/Authors :
Suzuki، نويسنده , , Junya and Sato، نويسنده , , Asami and Yamamoto، نويسنده , , Ryo and Asano، نويسنده , , Takashi and Shimosato، نويسنده , , Taku and Shima، نويسنده , , Hisashi and Kondo، نويسنده , , Junko N. and Yamashita، نويسنده , , Kenichi and Hashimoto، نويسنده , , Kenro and Fujino، نويسنده , , Tatsuya، نويسنده ,
Abstract :
An efficient matrix for matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) has been developed. The use of 2,4,6-trihydroxyacetophenone (THAP) on lithium-substituted zeolite has enabled ionization of low-molecular-weight compounds that are not detectable by conventional MALDI-MS. IR measurements and quantum-chemical calculations have also been carried out to understand the adsorption structure of THAP on zeolite. The mechanism of Li+ adduction from zeolite to THAP is also discussed. The important role of the water molecules adsorbed on the zeolite surface for the Li+ adduction from zeolite to THAP has been clarified.
