Protective effect of bamboo shoot oil on experimental nonbacterial prostatitis in rats

This study aim to investigate the protective effects of bamboo shoot oil (BSO) and its mechanisms on nonbacterial prostatitis (NBP). The anti-prostatitis effect of BSO were evaluated by prostate weight, acid phosphatase, density of lecithin corpuscles (DLCC), white blood cell count (WBC), and prostatic histomorphological parameters using Xiaozhiling-induced experimental NBP model in rats. The mechanisms of anti-prostatitis effect were assessed using functionally focused cDNA microarray and real-time PCR. BSO could significantly inhibited absolute prostate weight, prostate index, total acid phosphatase, prostatic acid phosphatase, WBC and the expression levels of thirty up-regulated genes, while BSO could significantly increased DLCC and the expression levels of fifteen down-regulated genes. Histologically, BSO treatment significantly suppressed the severity of the lesion in NBP-induced rats. Thus, BSO may be useful for treatment of NBP, as it may inhibits prostate inflammation in NBP patients by affecting the expression of inflammatory cytokines, their receptors, and related genes.