Synthesis, crystal structure and spectral properties of 6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide

In this work the synthesis of a new chromone (6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide) by a strategy performed in three steps is reported. The compound was characterized by NMR (1H and 13C) and EIMS and the structure was confirmed by single-crystal X-ray diffraction. The analysis of the X-ray determined that the molecule is built up from two rings, a chromone ring and a cyclohexene ring united by an amide spacer. This new chromone will be valuable for obtaining evidence about the importance of the exocyclic double bound on monoaminoxidase-B (MAO-B) inhibitory activity.