Author/Authors :
Wahaia، نويسنده , , Faustino and Kasalynas، نويسنده , , Irmantas and Seliuta، نويسنده , , Dalius and Molis، نويسنده , , Gediminas and Urbanowicz، نويسنده , , Andrzej and Carvalho Silva، نويسنده , , Catia D. and Carneiro، نويسنده , , Fatima and Valusis، نويسنده , , Gintaras and Granja، نويسنده , , Pedro L.، نويسنده ,
Abstract :
In this work, samples of non-neoplastic and adenocarcinoma-affected human colon tissue samples were analyzed using multipoint transmission time-domain THz spectroscopy (THz-TDS) to sort out the contrast-contributing factors other than water, the main contrast mechanism factor in in-vivo or in freshly excised bio-tissue. Solving the electromagnetic inverse problem through THz-TDS and, analyzing the transmittance spectra that yielded the frequency-dependent absorption coefficient α and refractive index n of non-neoplastic and neoplastic tissues, we show that it is possible to distinguish between non-neoplastic and neoplastic regions in paraffin-embedded dehydrated. Results and discussion are presented.
Keywords :
Paraffin-embedded samples , Colon adenocarcinoma , Pathologic staging , Tumor microenvironment , Time-domain terahertz spectroscopy
