Title of article
Synthesis and Antitubercular Activity of N3,N5-Diaryl-4-(5-arylisoxazol-3-yl)-1,4-dihydropyridine- 3,5-dicarboxamide
Author/Authors
Shafii، B. نويسنده 1Department of Medicinal Chemistry, Faculty of Pharmacy, Azad University, Tehran, Islamic Republic of Iran , , Amini، M. نويسنده 2Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 14174, Islamic Republic of Iran , , Akbarzadeh، T. نويسنده , , Shafiee، A. نويسنده ,
Issue Information
فصلنامه با شماره پیاپی 0 سال 2008
Pages
6
From page
323
To page
328
Abstract
5-Arylisoxazolyl-3-carboxaldehydes were condensed with N-aryl acetoaceta-mide and ammonium acetate in methanol to give N3,N5-diaryl-4-(5-arylisoxazol-3-yl)-1,4-dihydropyridine-3,5-dicarboxamides. All compounds were screened for their antitubercular activity against Mycobacterium tuberculosis (H37Rv). The results for new synthesized compounds showed a moderate activity in comparison to rifampicin.
Journal title
Journal of Sciences
Serial Year
2008
Journal title
Journal of Sciences
Record number
1983857
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