Title of article :
Nasal carriage rate of community- and hospital-acquired methicillin-resistant staphylococcus aureus in children, Kermanshah, Iran
Author/Authors :
Ghadiri، K. نويسنده Nosocomial disease research center, Kermanshah university of medical sciences. Ghadiri, K. , Ebrahimi، E. نويسنده Pediatric infectious disease subespecialist.Assosiated -professor of kermanshah university of medical sciences. Infectious disease research center Ebrahimi, E. , Akramipour، R نويسنده Pediatric Hematologist. Assistan professor of kermanshah university of medical sciences Akramipour, R , Rezaei ، M نويسنده Biostatistic department, social development and health promotion research center, kermanshah university of medical sciences Rezaei , M , Khazaei، S. نويسنده , , Afsharin، Ma نويسنده Infectious disease specialist. Assistan professor of kermanshah university of medical sciences Afsharin, Ma , Sedighi، I. نويسنده Pediatric infectious disease subespecialist. Hamadan unversity of medical sciences Sedighi, I. , Afsharian، Mi نويسنده MD.General physician Afsharian, Mi
Abstract :
Background:
Staphylococcus aureus (S.aureus) is an importantpathogen in human infections.Some strains of S.
aureusare methicillin-resistant (MRSA) andcause hospital- and community-acquired infections in children. The aims of
this study were to determine nasalcarriage rate of S. aureus and susceptibility pattern of this organism to some
antibioticsamong children in Kermanshah province, Iran.
Methods:
This was a cross-sectional study conducted in Kermanshah province, Iranfrom 2007 to 2008.Nasal swabs
were obtained from 274 children who were hospitalized in our university hospital at the time of admission and 219
children upon dischargetime.If result of nasal culture was positive at admission time they considered community
acquired and if result at admission time was negative but positive at discharge time they considered hospital acquired.
Antibiotic susceptibility patterns of S.aureuswere done by disk diffusion method and results were compared between
them.
Results:
In 55 patients out of 274 cases (20.07%), S. aureus was demonstrated upon admission (community-acquired).
In the remaining 219 cases, S. aureus was detected in 46 cases (21%) at discharge time (hospital-acquired). The rate of
methicillin-resistant S. aureus (MRSA) in community- and hospital-acquired infections were 96.4% and 95.7%,
respectively.We observed no statistical significance different in antibiotic resistance pattern between community
acquired and hospital – acquired S.aureus except for co-triomoxcazol (P=0.034).
Conclusion:
A high rate of MRSA in both community- and hospital-acquired infections were observed
