Title of article :
An efficient one-pot synthesis of tert-butyl 4-(alkylcarbamoyl)-1-(2,6-dimethylphenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carboxylate
Author/Authors :
خندان-باراني، خاطره نويسنده Khandan-Barani, Khatereh , مقصودلو، مالك طاهر نويسنده Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O.Box 98135-674, Zahedan, Iran. MalekTaher , Maghsoodlou MalekTaher Maghsoodlou , حسيني طباطبايي، محمد تقي نويسنده دانشگاه علوم پزشكي شهيد بهشتي, , , حسن ابادي، عليرضا نويسنده Department of Chemistry, Islamic Azad University, Zahedan Branch, P.O. Box 98135-978, Zahedan, Iran. Hassanabadi, Alireza , صفري، جيلا نويسنده Department of Chemistry, Islamic Azad University, Zahedan Branch, P.O. Box 98135-978, Zahedan, Iran Saffari, Jilla , كنگاني، مهرنوش نويسنده - ,
Abstract :
A convenient and efficient synthesis is described for the preparation of tert-butyl 4-(alkylcarbamoyl)-1-(2,6-dimethylphenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carboxylate via one-pot three-component reaction between tert-butyl isocyanide, dialkyl acetylenedicarboxylate and 2,6-dimethylphenyl isocyanate in dichloromethane without using any catalyst at room temperature in good yields
