Author/Authors :
عبدالمحمدي، شهرزاد نويسنده Department of Chemistry, Faculty of Science, East Tehran Branch, Islamic Azad University, PO Box 33955-163, Tehran, Iran and Fax: +98-21-3359 4332 Abdolmohammadi, Shahrzad , رفيعيا، فاطمه نويسنده Department of Chemistry, Faculty of Science, East Tehran Branch, Islamic Azad University, PO Box 33955-163, Tehran, Iran and Fax: +98-21-3359 4332 Rafieia, Fatemeh , حسينيان، اكرم نويسنده دانشگاه تهران ,
Abstract :
The zinc oxide nanoparticles thin-film (ZnO NPs thin-film) on glass substrate have been successfully prepared by the mild hydrothermal method and used as an efficient heterogeneous catalyst for the synthesis of dihydropyrimido[4,5-d]pyrimidinetrione derivatives via a three-component condensation of 6-aminouracils, aromatic aldehydes and urea in aqueous media at 70 ?C. The reusability of the catalyst, use of water as a green solvent and easy isolation of the products along with high yields of products are the advantages of the present protocol.
