Author/Authors :
Yang، نويسنده , , Guang-De and Li، نويسنده , , Cong and Zeng، نويسنده , , Ai-Guo and Qu، نويسنده , , Qinghui and Yang، نويسنده , , Xin and Bian، نويسنده , , Xiao-Li، نويسنده ,
Abstract :
The solubility of osthole in a binary system of ethanol and water was measured by UV spectrophotometry from 288.2 to 328.2 K. The solubility of osthole in the system increased with temperature. A synergistic effect appeared at x2 = 0.5527 (equivalent to 80% ethanol, v/v) binary mixtures. Solubility data correlated with a modified Apelblat equation. The enthalpy and entropy of solution of osthole were evaluated using van’t Hoff plots.
Keywords :
Osthole , Enthalpy of dissolution , solubility , Entropy of dissolution , Synergistic effect