Author/Authors :
Banagozar Mohammadi، Ali نويسنده Department of Internal Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. , , Noshad، Hamid نويسنده , , Ostadi، Ali نويسنده Department of Toxicology, Tabriz University of Medical Sciences, Tabriz, Iran. , , Ghaffari، Ali Reza نويسنده Philosophy and History of Medicine Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. , , Zaare Nahandi، Maryam نويسنده Internal Spesialist, Tabriz University of Medical Sciences, Tabriz, Iran. , , Banagozar Mohammadi، Ahad نويسنده Philosophy and History of Medicine Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. ,
Abstract :
Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency of contact. Management of these patients consists of conservative and palliative therapies to reduce the oxidative effects.
Case: The case was a 29-year-old girl with a Master of Sciences degree in genetics who worked in a university research center with previous history of depression. She had ingested 100cc of 30% Acrylamide solution for intentional suicide attempt. The patient was successfully managed using N-acetyl cysteine, vitamin C, and melatonin.
Conclusion: Early diagnosis and appropriate treatment with recommended agents together with supportive therapies can save the life of patients exposed to potentially lethal doses of acrylamide, although intentional or accidental.
