• Title of article

    Tetramethylguanidiniumtriflate catalyzed Henry reaction of isatins: An efficient synthesis of 3-hydroxy-3-(nitromethyl)indolin-2-one derivatives and their anti-diabetic activity

  • Author/Authors

    Youseftabar-Miri، Leila نويسنده Department of Chemistry, Izeh Branch, Islamic Azad University, Izeh, Iran , , Rafieirad، Maryam نويسنده Department of Biology, Izeh Branch, Islamic Azad University, Izeh, Iran. ,

  • Issue Information
    فصلنامه با شماره پیاپی 0 سال 2015
  • Pages
    5
  • From page
    15
  • To page
    19
  • Abstract
    The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity.
  • Journal title
    Iranian Journal of Catalysis
  • Serial Year
    2015
  • Journal title
    Iranian Journal of Catalysis
  • Record number

    2002127